In this last chapter the diversity of integration strategies and building blocks within the field of nanoarchitectonics is illustrated by describing a variety of different physicochemical systems ranging from surface-confined macromolecules to self-assembled supramolecular colloids. The resulting concerted functionalities and synergistic effects coming from the rational integration of different building blocks highlight the importance of the nanoarchitectonics point of view on the design and fabrication of new materials for confronting complex problems with creative solutions in areas comprising health, environment, and energy.