Published in
De Gruyter, Clinical Chemistry and Laboratory Medicine, 12(48), 2010
Links
- ORCID
- ORCID
- ORCID
- De Gruyter
- [ntur.lib.ntu.edu.tw]
- [www.ncbi.nlm.nih.gov] | PDF
- [ntur.lib.ntu.edu.tw]
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [europepmc.org] | PDF
Tools
The Relationship between Aminoterminal Propeptide of Type Iii Procollagen and Heart Rate Variability Parameters in Heart Failure Patients: A Potential Serum Marker to Evaluate Cardiac Autonomic Control and Sudden Cardiac Death
,
林彥宏;羅孟宗;林鴻儒;吳彥雯;許榮彬;趙嘉倫;許秀卿;王拔群;吳允升;王水深;簡國龍;何奕倫;陳明豐,
Chen Lin,
Men-Tzung Lo,
Hung-Ju Lin,
Yen-Wen Wu,
Ron-Bin Hsu,
Chia-Lun Chao,
Hsiu-Ching Hsu,
Pa-Chun Wang,
Vin-Cent Wu,
Ron Bin Hsu,
Shoei-Shen Wang,
Chi-Ming Lee,
Kuo-Liong Chien
and other authors.
Full text: Download
Abstract
Background: Cardiac extra-cellular matrix (ECM) fibrosis plays an important role in the pathophysiology of heart failure (HF). It may provide electrical heterogeneity and a substrate for arrhythmogenicity, which may cause sudden cardiac death (SCD). Methods: Twenty-one patients with manifestations of HF and a left ventricular ejection fraction (LVEF) 50 ms (pNN50) (r=-0. 528, p=0.014), percentage of adjacent NN interval differences >20 ms (pNN20) (r=-0.545, p=0.002), very low frequency (VLF) (r=-0.490, p=0.024), low frequency (LF) (r=- 0.491, p=0. 024), and high frequency (HF) (r=-0.513, p=0.018 ). PINP, MMP-2, -9, TIMP- 1 were not correlated with time-and frequency-domain analysis of HRV. Conclusions: PIIINP was significantly correlated with time- and frequency- domain analysis of HRV in HF patients. PIIINP is a potential serological marker to evaluate cardiac autonomic control and risk of SCD in HF patients. ; 附設醫院內科部 ; 醫學院附設醫院 ; 期刊論文