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Elsevier, Clinica Chimica Acta, 1-2(409), p. 96-99

DOI: 10.1016/j.cca.2009.09.001

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The Relationship between Serum Galectin-3 and Serum Markers of Cardiac Extracellular Matrix Turnover in Heart Failure Patients

Journal article published in 2009 by 林彥宏;林亮宇;吳彥雯;簡國龍;李啟明;許榮彬;趙嘉倫;王水深;謝月貞;廖玲巧;何奕倫;陳明豐, Yen-Wen Wu, Kuo-Liong Chien ORCID, Chi-Ming Lee, Ron-Bin Hsu, Chia-Lun Chao, Yen-Hung;Lin Lian-Yu;Wu Yen-Wen;Chien Kuo-Liong;Lee Chii-Ming;Hsu Ron-Bin;Chao Chia-Lun;Wang Shoei-Shen;Hsein Yenh-Chen;Liao Lin-Chu;Ho Yi-Lwun;Chen Ming-Fong Lin ORCID, Shoei-Shen Wang, Yenh-Chen Hsein, Lin-Chu Liao, Yi-Lwun Ho ORCID, Ming-Fong Chen, YH;Lin LY;Wu YW;Chien KL;Lee CM;Hsu RB;Chao CL;Wang SS;Hsein YC;Liah LC;Ho YL;Chen Lin
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Background: A growing body of evidence links macrophage activation and fibrosis to the pathogenesis of heart failure (HF). Galectin-3 is one of the most likely mediators between macrophage activation and myocardial fibrosis. However, the exact relationship is unknown in humans. We assessed the impact of galectin-3 on serum markers of cardiac extracellular matrix (ECM) turnover in HF patients. Methods: Patients with HF manifestations and a left ventricular ejection fraction (LVEF)