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American Association for Cancer Research, Clinical Cancer Research, 10(28), p. 1996-1998, 2022

DOI: 10.1158/1078-0432.ccr-22-0214

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Standing Watch: Immune Activation and Failure in Melanoma Sentinel Lymph Nodes

Journal article published in 2022 by Amanda W. Lund ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

SummaryAn unbiased approach to map the sentinel lymph node landscape reveals progressive immune dysfunction associated with micrometastasis in patients with stage I–III cutaneous melanoma. Evidence of tumor-induced lymph node dysfunction may motivate new hypotheses for neoadjuvant therapy with potential to reinvigorate endogenous antitumor immunity.See related article by Yaddanapudi et al., p. 2069