Dissemin is shutting down on January 1st, 2025

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European Centre for Disease Prevention and Control, Eurosurveillance, 10(27), 2022

DOI: 10.2807/1560-7917.es.2022.27.10.2200181

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Molecular epidemiology of the SARS-CoV-2 variant Omicron BA.2 sub-lineage in Denmark, 29 November 2021 to 2 January 2022

Journal article published in 2022 by Jannik Fonager ORCID, Marc Bennedbæk ORCID, Peter Bager, Jan Wohlfahrt, Kirsten Maren Ellegaard, Anna Cäcilia Ingham ORCID, Sofie Marie Edslev, Marc Stegger ORCID, Raphael Niklaus Sieber ORCID, Ria Lassauniere ORCID, Anders Fomsgaard ORCID, Troels Lillebaek ORCID, Christina Wiid Svarrer, Frederik Trier Møller ORCID, Camilla Holten Møller ORCID and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Following emergence of the SARS-CoV-2 variant Omicron in November 2021, the dominant BA.1 sub-lineage was replaced by the BA.2 sub-lineage in Denmark. We analysed the first 2,623 BA.2 cases from 29 November 2021 to 2 January 2022. No epidemiological or clinical differences were found between individuals infected with BA.1 versus BA.2. Phylogenetic analyses showed a geographic east-to-west transmission of BA.2 from the Capital Region with clusters expanding after the Christmas holidays. Mutational analysis shows distinct differences between BA.1 and BA.2.