Published in
Royal Society of Chemistry, RSC Advances, 15(12), p. 9494-9500, 2022
DOI: 10.1039/d2ra01396g
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Structural transformation of methasterone with Cunninghamella blakesleeana and Macrophomina phaseolina
Journal article published in 2022 by
Muhammad Aamer,
Mahwish Siddiqui,
Almas Jabeen,
Rimsha Irshad,
Farooq-Ahmad Khan,
Atia-Tul-Wahab,
M. Iqbal Choudhary 
,
Yan Wang
,
Yan Wang
This paper is made freely available by the publisher.
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Abstract
Fungal transformation of methasterone resulted in six products (2–7). 2–5, and 7 were identified as new. Substrate 1 showed remarkable anti-inflammatory activity but was cytotoxic. Products 2 and 7 showed moderate activity but were non-cytotoxic.