Published in
Royal Society of Chemistry, Chemical Science, 19(13), p. 5767-5773, 2022
DOI: 10.1039/d2sc00636g
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Organocatalytic discrimination of non-directing aryl and heteroaryl groups: enantioselective synthesis of bioactive indole-containing triarylmethanes
Journal article published in 2022 by
Qiaolin Yan,
Meng Duan,
Cien Chen,
Zhiqing Deng 
,
Mandi Wu,
Peiyuan Yu ,
Ming-Liang He ,
Guangyu Zhu ,
K. N. Houk ,
Jianwei Sun
,
Mandi Wu,
Peiyuan Yu ,
Ming-Liang He ,
Guangyu Zhu ,
K. N. Houk ,
Jianwei Sun
This paper is made freely available by the publisher.
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Abstract
Excellent enantiodiscrimination between aryl and heteroaryl groups without a directing group has been achieved with organocatalysis. The highly enantioenriched triarylmethane products exhibit anticancer and antiviral activities.