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American Thoracic Society, American Journal of Respiratory and Critical Care Medicine, 5(180), p. 454-461, 2009

DOI: 10.1164/rccm.200901-0115oc

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Endothelial Colony-forming Cells from Preterm Infants Are Increased and More Susceptible to Hyperoxia

Journal article published in 2009 by Christopher D. Baker, Sharon L. Ryan, David A. Ingram, Gregory J. Seedorf, Steven H. Abman, Vivek Balasubramaniam
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Rationale: Preterm birth and hyperoxic exposure increase the risk for bronchopulmonary dysplasia (BPD), a chronic lung disease characterized by impaired vascular and alveolar growth. Endothelial progenitor cells, such as self-renewing highly proliferative endothelial colony-forming cells (ECFCs), may participate in vascular repair. The effect of hyperoxia on ECFC growth is unknown.