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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 5(66), 2022

DOI: 10.1128/aac.02079-21

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Selective Inhibition of Plasmodium falciparum ATPase 6 by Artemisinins and Identification of New Classes of Inhibitors after Expression in Yeast

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Treatment failures with artemisinin combination therapies (ACTs) threaten global efforts to eradicate malaria. They highlight the importance of identifying drug targets and new inhibitors and of studying how existing antimalarial classes work.