Abstract Methacrylic acid based microgels have got much consideration in the last two decades because of their potential uses in different fields owing to their responsive behaviour towards external stimuli. Synthesis, properties and uses of methacrylic acid based microgels and their hybrids have been critically reviewed in this article. With minute change in external stimuli such as pH and ionic strength of medium, these microgels show quick swelling/deswelling reversibly. The methacrylic acid based microgels have been widely reported for applications in the area of nanotechnology, drug delivery, sensing and catalysis due to their responsive behaviour. A critical review of current research development in this field along with upcoming perception is presented here. This discussion is concluded with proposed probable future studies for additional growth in this field of research.