Published in
Lippincott, Williams & Wilkins, Journal of Hypertension, 6(28), p. 1313-1320, 2010
DOI: 10.1097/hjh.0b013e328337a9fd
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Reinforcement of the adrenergic overdrive in the metabolic syndrome complicated by obstructive sleep apnea
Journal article published in 2010 by
Guido Grassi,
Gino Seravalle 
,
Fal Quarti Trevano,
Claudia Mineo,
Laura Lonati,
Rl Facchetti,
Giuseppe Mancia
,
Fal Quarti Trevano,
Claudia Mineo,
Laura Lonati,
Rl Facchetti,
Giuseppe Mancia
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Abstract
Metabolic syndrome is characterized by a marked sympathetic overactivity. It is unknown, however, whether the neuroadrenergic activation can be ascribed to obstructive sleep apnoea (OSA), OSA exerts potentiating effects on the metabolic syndrome-related sympathetic activation and reflex/metabolic variables (insulin resistance) participate at the phenomenon.