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MDPI, Journal of Clinical Medicine, 15(11), p. 4564, 2022

DOI: 10.3390/jcm11154564

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Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex

Journal article published in 2022 by Małgorzata Foryś-Basiejko ORCID, Katarzyna Kotulska, Agnieszka Maryniak ORCID, Agata Siłuszyk ORCID, Monika Szkop, Julita Borkowska, Monika Sugalska, Jagoda Głowacka-Walas ORCID, Sergiusz Jóźwiak
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

This paper aimed to assess language development in infants and toddlers with tuberous sclerosis complex (TSC) and epilepsy, which increase the risk of autism spectrum disorder. We assessed language development in 61 patients with TSC at 8–36 months using a standardized Speech Development and Communication Inventory tool. The results showed differences in outcomes due to the duration of the seizures and the number of drugs (pFDR = 0.007 **—pFDR = 0.037 *). Children with TSC with longer epilepsy duration and receiving more antiepileptic drugs have a greater risk of language development delay.