AbstractBackgroundWork can have a major positive impact on health and wellbeing. Employment of kidney transplant recipients (KTR) of working age is much lower than in the general population. The first aim of this study was to examine the impact of a preemptive kidney transplantation (PKT) on employment, in addition to other possible influencing factors. The second aim was to explore differences in work ability, absenteeism and work performance among employed KTR with different types of transplantations.MethodsA cross‐sectional survey study was conducted between 2018 and 2019 in nine Dutch hospitals. PKT as potential predictor of employment was examined. Furthermore, work ability, absenteeism and loss of work performance were compared between employed preemptive recipients with a living donor (L‐PKT) and non‐preemptive recipients with a living donor (L‐nPKT) and with a deceased donor (D‐nPKT).ResultsTwo hundred and twenty four KTR participated; 71% reported having paid work. Paid work was more common among PKT recipients (82% vs. 65% in L‐nPKT and 55% in D‐nPKT) and recipients who were younger (OR .950, 95%CI .913–.989), had no comorbidities (1 comorbidity: OR .397, 95%CI .167–.942; 2 comorbidities: OR .347, 95%CI .142–.844), had less fatigue (OR .974, 95%CI .962–.987) and had mentally demanding work tasks (only in comparison with physically demanding tasks, OR .342, 95%CI .145–.806). If recipients were employed, D‐nPKT recipients worked fewer hours (mean 24.6±11.3 vs. PKT 31.1±9.6, L‐nPKT 30.1±9.5) and D‐nPKT and L‐nPKT recipients received more often supplemental disability benefits (32 and 33.3%, respectively) compared to PKT recipients (9.9%). No differences were found for self‐reported ability to work, sick leave (absenteeism) and loss of work performance with the exception of limitations in functioning at work.ConclusionsPreemptive kidney transplantation recipients with a kidney from a living donor are employed more often, work more hours per week (only in comparison with D‐nPKT) and have a partial disability benefit less often than nPKT recipients. More knowledge regarding treatments supporting sustainable participation in the labor force is needed as work has a positive impact on recipients’ health and wellbeing and is also beneficial for society as a whole.