The 12 May 2008 the Sichuan earthquake was one of the worst natural disasters in China. Here, we present a detailed picture of the epicentral area inferred geophysical data. Based on the analysis of teleseismic data acquired by a dense seismic network, we highlight an abrupt 20 km Moho offset between the Sichuan Basin and the Tibetan plateau and a horizontal discontinuity at similar to 15 km depth, which may connect with the ruptured zone of the 2008 event. We obtain low mean crustal velocity ratios, which suggest the absence of a thick and extensive zone of partial melt within the crust beneath the eastern part of the Songpan-Garze Terrane. All our data support the idea that the Longmen Shan range mark a zone of active strain localization due to the rigid Yangtze craton resisting eastward displacement of the Tibetan Plateau.