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American Physiological Society, Journal of Applied Physiology, 1(136), p. 13-22, 2024

DOI: 10.1152/japplphysiol.00283.2023

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Type 2 diabetes exacerbates changes in blood pressure-independent arterial stiffness: cross-sectional and longitudinal evidence from the SUMMIT study

Journal article published in 2024 by Kunihiko Aizawa ORCID, Phillip E. Gates, David M. Mawson, Francesco Casanova, Kim M. Gooding, Suzy V. Hope, Isabel Goncalves ORCID, Jan Nilsson, Faisel Khan, Helen M. Colhoun ORCID, Andrea Natali, Carlo Palombo ORCID, Angela C. Shore
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

We demonstrate in this study a greater BP-independent arterial stiffness β0 in people with type 2 diabetes (T2DM) compared to those without, and also a greater change in β0 over 3 yr in people with T2DM than those without. These findings suggest that the intrinsic properties of the arterial wall may change in a different and more detrimental way in people with T2DM and likely represents accumulation of cardiovascular risk.