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American Institute of Physics, Structural Dynamics, 4(2), p. 041717, 2015

DOI: 10.1063/1.4922648

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Simple convergent-nozzle aerosol injector for single-particle diffractive imaging with X-ray free-electron lasers

Journal article published in 2015 by R. A. Kirian, S. Awel, N. Eckerskorn, H. Fleckenstein, M. Wiedorn, L. Adriano, S. Bajt, M. Barthelmess, R. Bean, Kenneth R. Beyerlein, Leonard M. G. Chavas, M. Domaracky, M. Heymann ORCID, Daniel A. Horke, J. Knoska ORCID and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

SeriesInformation ; Structural dynamics 2(4), 041717(2015). doi:10.1063/1.4922648 ; Abstract ; A major challenge in high-resolution x-ray free-electron laser-based coherent diffractive imaging is the development of aerosol injectors that can efficiently deliver particles to the peak intensity of the focused X-ray beam. Here, we consider the use of a simple convergent-orifice nozzle for producing tightly focused beams of particles. Through optical imaging we show that 0.5 μm particles can be focused to a full-width at half maximum diameter of 4.2 μm, and we demonstrate the use of such a nozzle for injecting viruses into a micro-focused soft-X-ray FEL beam. ; Other ; Published by AIP Publishing LLC, Melville, NY