Published in
American Society for Microbiology, Journal of Virology, 18(96), 2022
DOI: 10.1128/jvi.01011-22
Links
Tools
HIV-1 Preintegration Complex Preferentially Integrates the Viral DNA into Nucleosomes Containing Trimethylated Histone 3-Lysine 36 Modification and Flanking Linker DNA
Journal article published in 2022 by
Nicklas Sapp,
Nathaniel Burge,
Khan Cox,
Prem Prakash,
Muthukumar Balasubramaniam,
Santosh Thapa,
Devin Christensen,
Min Li,
Jared Linderberger,
Mamuka Kvaratskhelia 
,
Jui Pandhare,
Robert Craigie,
Michael G. Poirier,
Chandravanu Dash
,
Jui Pandhare,
Robert Craigie,
Michael G. Poirier,
Chandravanu Dash
This paper is made freely available by the publisher.
Full text: Download
Data provided by 
Abstract
HIV-1 infection is dependent on integration of the viral DNA into the host chromosomes. The preintegration complex (PIC) containing the viral DNA, the virally encoded integrase (IN) enzyme, and other viral/host factors carries out HIV-1 integration.