The Antibacterial Type VII Secretion System of Bacillus subtilis: Structure and Interactions of the Pseudokinase YukC/EssB
Journal article published in 2022 by
Matteo Tassinari 
,
Thierry Doan ,
Marco Bellinzoni ,
Maïalene Chabalier,
Mathilde Ben-Assaya,
Mariano Martinez ,
Quentin Gaday,
Pedro M. Alzari ,
Eric Cascales ,
Rémi Fronzes ,
Francesca Gubellini
,
Thierry Doan ,
Marco Bellinzoni ,
Maïalene Chabalier,
Mathilde Ben-Assaya,
Mariano Martinez ,
Quentin Gaday,
Pedro M. Alzari ,
Eric Cascales ,
Rémi Fronzes ,
Francesca Gubellini
This paper is made freely available by the publisher.
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Abstract
Type VII secretion systems mediate protein extrusion from Gram-positive bacteria and are classified as T7SSa and T7SSb in Actinobacteria and in Firmicutes , respectively. Despite the genetic divergence of T7SSa and T7SSb, the high degree of structural similarity of their WXG100 substrates suggests similar secretion mechanisms.