Published in
American Society for Microbiology, Microbiology Spectrum, 5(10), 2022
DOI: 10.1128/spectrum.02365-22
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In Vitro and In Vivo Antimicrobial Activity of Hypochlorous Acid against Drug-Resistant and Biofilm-Producing Strains
Journal article published in 2022 by
Marta Palau 
,
Estela Muñoz ,
Enric Lujan ,
Nieves Larrosa ,
Xavier Gomis ,
Ester Márquez ,
Oscar Len ,
Benito Almirante ,
Jordi Abellà ,
Sergi Colominas ,
Joan Gavaldà
,
Estela Muñoz ,
Enric Lujan ,
Nieves Larrosa ,
Xavier Gomis ,
Ester Márquez ,
Oscar Len ,
Benito Almirante ,
Jordi Abellà ,
Sergi Colominas ,
Joan Gavaldà
This paper is made freely available by the publisher.
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Abstract
Currently, drug-resistant infections are increasing and there are fewer antibiotics available to treat them. Therefore, there is an urgent need to find new antibiotics and nonantimicrobial strategies to treat these infections. We present a new nonantibiotic strategy based on hypochlorous acid generation to treat long-term catheter-related and chronic wounds infections.