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American Society for Microbiology, Microbiology Spectrum, 5(10), 2022

DOI: 10.1128/spectrum.02365-22

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In Vitro and In Vivo Antimicrobial Activity of Hypochlorous Acid against Drug-Resistant and Biofilm-Producing Strains

Journal article published in 2022 by Marta Palau ORCID, Estela Muñoz ORCID, Enric Lujan ORCID, Nieves Larrosa ORCID, Xavier Gomis ORCID, Ester Márquez ORCID, Oscar Len ORCID, Benito Almirante ORCID, Jordi Abellà ORCID, Sergi Colominas ORCID, Joan Gavaldà ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Currently, drug-resistant infections are increasing and there are fewer antibiotics available to treat them. Therefore, there is an urgent need to find new antibiotics and nonantimicrobial strategies to treat these infections. We present a new nonantibiotic strategy based on hypochlorous acid generation to treat long-term catheter-related and chronic wounds infections.