Published in
American Society for Microbiology, Infection and Immunity, 3(90), 2022
DOI: 10.1128/iai.00013-22
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Tumor Necrosis Factor Alpha Contributes to Inflammatory Pathology in the Placenta during Brucella abortus Infection
Journal article published in 2022 by
April Y. Tsai,
Mariana X. Byndloss 
,
Núbia Seyffert ,
Maria G. Winter,
Briana M. Young,
Renée M. Tsolis
,
Núbia Seyffert ,
Maria G. Winter,
Briana M. Young,
Renée M. Tsolis
This paper is made freely available by the publisher.
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Abstract
Research on Brucella pathogenesis has focused primarily on its ability to cause persistent intracellular infection of the mononuclear phagocyte system. At these sites, Brucella abortus evades innate immunity, which results in low-level inflammation and chronic infection of phagocytes.