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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 11(66), 2022

DOI: 10.1128/aac.00420-22

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Dephospho-Coenzyme A Kinase Is an Exploitable Drug Target against Plasmodium falciparum: Identification of Selective Inhibitors by High-Throughput Screening of a Large Chemical Compound Library

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Malaria is a mosquito-borne fatal infectious disease that affects humans and is caused by Plasmodium parasites, primarily Plasmodium falciparum . Widespread drug resistance compels us to discover novel compounds and alternative drug discovery targets.