American Association for Cancer Research, Cancer Discovery, 11(12), p. 2496-2497, 2022
DOI: 10.1158/2159-8290.cd-22-0852
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Summary: Martini and colleagues performed genetic ancestry estimation on a unique international triple-negative breast cancer (TNBC) study enriched for participants with African ancestry. They identified gene signatures indicative of ancestry in race-associated TNBC and found ancestry-associated immunologic differences that may contribute to racial disparities in breast cancer. See related article by Martini et al., p. 2530 (5).