Dissemin is shutting down on January 1st, 2025

Published in

Rockefeller University Press, Journal of Cell Biology, 12(221), 2022

DOI: 10.1083/jcb.202211001

Links

Tools

Export citation

Search in Google Scholar

Letting go: Dishevelled phase separation recruits Axin to stabilize β-catenin

Journal article published in 2022 by Rachel L. Babcock ORCID, Kevin Pruitt ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Red circle
Postprint: archiving forbidden
Green circle
Published version: archiving allowed
Data provided by SHERPA/RoMEO

Abstract

Dishevelled exerts a molecular force that guides cell fate, but how it does so remains enigmatic. In this issue, Kang et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202205069) show Dvl2 undergoes liquid–liquid phase separation to stabilize β-catenin by pulling Axin into its biomolecular condensate at the plasma membrane.