Published in
American Society for Microbiology, Microbiology Spectrum, 6(10), 2022
DOI: 10.1128/spectrum.02842-22
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Intestinal Dominance by Multidrug-Resistant Bacteria in Pediatric Liver Transplant Patients
Journal article published in 2022 by
Elias Dahdouh 
,
Lorena Fernández-Tomé,
Emilio Cendejas-Bueno,
Guillermo Ruiz-Carrascoso ,
Cristina Schüffelmann,
María Alós-Díez,
Fernando Lázaro-Perona ,
Mercedes Castro-Martínez,
Luis Escosa-García,
Sonia Jiménez-Rodríguez,
Loreto Hierro-Llanillo,
Jesús Mingorance
,
Lorena Fernández-Tomé,
Emilio Cendejas-Bueno,
Guillermo Ruiz-Carrascoso ,
Cristina Schüffelmann,
María Alós-Díez,
Fernando Lázaro-Perona ,
Mercedes Castro-Martínez,
Luis Escosa-García,
Sonia Jiménez-Rodríguez,
Loreto Hierro-Llanillo,
Jesús Mingorance
This paper is made freely available by the publisher.
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Abstract
In this study, we track the relative intestinal loads of antibiotic resistance genes among pediatric liver transplant patients and determine the relationship between this load, antibiotic consumption, and infections caused by antibiotic-resistant organisms. We demonstrate that the consumption of broad spectrum antibiotics increase this load and decrease the gut microbial diversity among these patients.