Genomic Variation across a Clinical Cryptococcus Population Linked to Disease Outcome
Journal article published in 2022 by
Poppy Sephton-Clark,
Jennifer L. Tenor,
Dena L. Toffaletti,
Nancy Meyers,
Charles Giamberardino,
Síle F. Molloy,
Julia R. Palmucci,
Adrienne Chan,
Tarsizio Chikaonda 
,
Robert Heyderman,
Mina Hosseinipour,
Newton Kalata,
Cecilia Kanyama,
Christopher Kukacha,
Duncan Lupiya
and other authors.
,
Robert Heyderman,
Mina Hosseinipour,
Newton Kalata,
Cecilia Kanyama,
Christopher Kukacha,
Duncan Lupiya
and other authors.
This paper is made freely available by the publisher.
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Abstract
Infection outcomes for cryptococcosis, most commonly caused byC. neoformans, are influenced by host immune responses as well as by host and pathogen genetics. Infecting yeast isolates are genetically diverse; however, we lack a deep understanding of how this diversity impacts patient outcomes.