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Royal Society of Chemistry, Chemical Science, 22(13), p. 6599-6609, 2022

DOI: 10.1039/d2sc00555g

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Covalent labeling of a chromatin reader domain using proximity-reactive cyclic peptides

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

We describe the development of covalent cyclic peptide ligands which target a chromatin methylation reader domain using a proximity-reactive sulfonyl fluoride moiety.