Published in
American Society for Microbiology, Microbiology Spectrum, 6(10), 2022
DOI: 10.1128/spectrum.01424-22
Links
Tools
Generation of an Attenuated Chimeric Bat Influenza A Virus Live-Vaccine Prototype
Journal article published in 2022 by
Wei Ran,
Jacob Schön,
Kevin Ciminski 
,
Julian Kraft,
Susanne Kessler ,
Sophie Euchner,
Donata Hoffmann,
Anne Pohlmann,
Martin Beer ,
Martin Schwemmle ,
Sebastian Giese
,
Julian Kraft,
Susanne Kessler ,
Sophie Euchner,
Donata Hoffmann,
Anne Pohlmann,
Martin Beer ,
Martin Schwemmle ,
Sebastian Giese
This paper is made freely available by the publisher.
Full text: Download
Data provided by 
Abstract
Recurring influenza A virus outbreaks in livestock, particularly in swine and chickens, pose a constant threat to humans. Live attenuated influenza vaccines (LAIVs) might be a potent tool to prevent epizootic outbreaks and the resulting human IAV infections; however, LAIVs have several disadvantages, especially in terms of reassortment with circulating IAVs.