Published in

American Society for Microbiology, Journal of Virology, 24(96), 2022

DOI: 10.1128/jvi.01082-22

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Antibody Recognition of CD4-Induced Open HIV-1 Env Trimers

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

The RV144 HIV-1 clinical vaccination trial showed modest protection against viral infection. Antibody responses to the V1V2 region of HIV-1 Env gp120 were correlated inversely with the risk of infection, and data from three other clinical vaccine trials suggested a similar signal.