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Cell Press, Current Biology, 12(19), p. R496-R498, 2009

DOI: 10.1016/j.cub.2009.04.049

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Antigenic Variation: Extending the Reach of Telomeric Silencing

Journal article published in 2009 by David Horn ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Immune evasion in the parasitic African trypanosome relies upon the silencing of variant surface glycoprotein genes that are found adjacent to telomeres. Work on the RAP1 telomere-binding protein now indicates that silencing spreads over a sufficient distance to repress these genes.