Abstract We draw a multimessenger picture of J1048+7143, a flat-spectrum radio quasar known to show quasiperiodic oscillations in the γ-ray regime. We generate the adaptively binned Fermi Large Area Telescope light curve of this source above 168 MeV to find three major γ-ray flares of the source, such that each of the three flares consists of two sharp subflares. Based on radio interferometric imaging data taken with the Very Large Array, we find that the kiloparsec-scale jet is directed west, while our analysis of 8.6 GHz very long baseline interferometry data, mostly taken with the Very Long Baseline Array, revealed signatures of two parsec-scale jets, one pointing east, one pointing south. We suggest that the misalignment of the kiloparsec- and parsec-scale jets is a revealing signature of jet precession. We also analyze the 5 GHz total flux density curve of J1048+7143 taken with the Nanshan (Ur) and RATAN-600 single-dish radio telescopes and find two complete radio flares, lagging slightly behind the γ-ray flares. We model the timing of γ-ray flares as a signature of the spin–orbit precession in a supermassive black hole binary, and find that the binary could merge in the next ∼60–80 yr. We show that both pulsar timing arrays and the planned Laser Interferometer Space Antenna lack sensitivity and frequency coverage to detect the hypothetical supermassive black hole binary in J1048+7143. We argue that the identification of sources similar to J1048+7143 plays a key role in revealing periodic high-energy sources in the distant universe.