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American Association for the Advancement of Science, Science Advances, 39(7), 2021

DOI: 10.1126/sciadv.abi7514

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A common genetic variant of a mitochondrial RNA processing enzyme predisposes to insulin resistance

Journal article published in 2021 by Giulia Rossetti ORCID, Judith A. Ermer ORCID, Maike Stentenbach ORCID, Stefan J. Siira ORCID, Tara R. Richman, Dusanka Milenkovic ORCID, Kara L. Perks, Laetitia A. Hughes ORCID, Emma Jamieson ORCID, Gulibaikelamu Xiafukaiti ORCID, Natalie C. Ward ORCID, Satoru Takahashi ORCID, Nicola Gray ORCID, Helena M. Viola ORCID, Livia C. Hool ORCID and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

A variant in an RNA processing enzyme predisposes to insulin resistance by reducing calcium release and insulin secretion.