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American Society for Microbiology, Microbiology Spectrum, 1(11), 2023

DOI: 10.1128/spectrum.01943-22

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Inhibitors of One or More Cellular Aurora Kinases Impair the Replication of Herpes Simplex Virus 1 and Other DNA and RNA Viruses with Diverse Genomes and Life Cycles

Journal article published in 2023 by Cindy Y. Ly, Jessica Pfannenstiel, Anil Pant, Zhilong Yang ORCID, Anthony R. Fehr ORCID, Maxim S. Rodzkin, David J. Davido ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

We have demonstrated that aurora kinases play a role during HSV-1 lytic infection. Three aurora kinase inhibitors significantly impaired HSV-1 immediate-early gene expression.