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Springer Nature [academic journals on nature.com], British Journal of Cancer, 7(80), p. 1103-1106, 1999

DOI: 10.1038/sj.bjc.6690471

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Human herpes virus-6 seroprevalence and leukaemias: a case-control study

Journal article published in 1999 by G. Gentile, A. Mele, G. Ragona, A. Faggioni, C. Zompetta, M. E. Tosti ORCID, G. Visani, G. Castelli, A. Pulsoni, B. Monarca, P. Martino, F. Mandelli
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The relationships between acute myeloid leukaemia (AML), acute lymphocytic leukaemia (ALL), chronic myeloid leukaemia (CML) and refractory anaemia with excess of blasts (RAEB) and human herpes virus (HHV)-6 antibody level were investigated in a multicentre case-control study. An association between increased HHV-6 seropositivity and geometric mean titre ratio with AML was shown: P for trend = 0.022, adjusted odds ratio 1.20, 95% confidence interval 1.07-1.33 respectively. No association was found between HHV-6 and ALL, CML or RAEB.