Published in
Nature Research, npj Microgravity, 1(9), 2023
DOI: 10.1038/s41526-023-00267-2
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External to internal cranial perfusion shifts during simulated weightlessness: Results from a randomized cross-over trial
Journal article published in 2023 by
Alessa L. Boschert 
,
Peter Gauger,
Anja Bach,
Darius Gerlach ,
Bernd Johannes,
Jens Jordan ,
Zhili Li,
David Elmenhorst ,
Andreas Bauer ,
Karina Marshall-Goebel ,
Jens Tank,
Jochen Zange,
Jörn Rittweger
,
Peter Gauger,
Anja Bach,
Darius Gerlach ,
Bernd Johannes,
Jens Jordan ,
Zhili Li,
David Elmenhorst ,
Andreas Bauer ,
Karina Marshall-Goebel ,
Jens Tank,
Jochen Zange,
Jörn Rittweger
This paper is made freely available by the publisher.
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Abstract
AbstractThe exact pathophysiology of the spaceflight-associated neuro-ocular syndrome (SANS) has so far not been completely elucidated. In this study we assessed the effect of acute head-down tilt position on the mean flow of the intra- and extracranial vessels. Our results suggest a shift from the external to the internal system that might play an important role in the pathomechanism of SANS.