Sunflower is one of the major oil crops in the world. Diseases such as sunflower downy mildew (Plasmopara halstedii (Farl.) Berl. et de Toni) constitute a significant risk factor during sunflower production. Integrated pest management (IPM) is considered an essential tool against sunflower downy mildew; however, the pathogen variability repeatedly affects the efficacy of control measures. This article evaluates some vital elements of the management of sunflower downy mildew disease and analyzes current challenges. In addition, we outlined the options for the future integration of recent research and achievements related to sunflower downy mildew to achieve more sustainable sunflower production. Finally, a SWOT analysis was performed to consider internal factors, such as strengths (S) and weaknesses (W), and external factors, such as opportunities (O) and threats (T) connected to the topic.