Abstract We report the observations of periodic nulling in PSR B2111+46 at 1250 MHz with the Five-hundred-meter Aperture Spherical radio Telescope (FAST). The nulling fractions (NF) as well as nulling period of this pulsar were calculated. The NF and nulling period are 17% ± 1% and 62.49 ± 0.99 P ₁, respectively, and the periodic nulling shows variations in periodicity with time. The durations of each consecutive burst and nulling were investigated, which show that the power-law distribution and the indices are −1.11 ± 0.04 and −2.08 ± 0.23. In the observed frequency band, the width of the profile is narrowed with the increase in frequency, and the degree of polarization has no obvious trend with the increase in frequency. We discovered a weak emission component in front of the leading component of this triple-type profile pulsar that was not observed in other bands and by other telescopes. With the fitting of rotation vector model, we obtained that the angles of the magnetic inclination α and the line of sight ζ are ∼13.°0 and ∼11.°6, respectively. The high-sensitivity observation of FAST improves our understanding of the emission of this pulsar.