Published in

Oxford University Press, Nucleic Acids Research, Database(37), p. D211-D215, 2009

DOI: 10.1093/nar/gkn785

Links

Tools

Export citation

Search in Google Scholar

InterPro: the integrative protein signature database

Journal article published in 2009 by Rolf Apweiler, Sarah Apweiler R. Attwood T. K. Bairoch A. Bateman A. Binns D. Bork P. Das U. Daugherty L. Duquenne L. Finn R. Gough J. Haft D. Hulo N. Kahn D. Kelly E. Laugraud A. Letunic I. Lonsdale D. Lopez R. Madera M. Maslen J. McAnulla C. McDowall J. Mistry J. Mitch Hunter, Teresa K. Attwood, Amos Bairoch, Alex Bateman ORCID, David Binns, Peer Bork ORCID, Ujjwal Das, Louise Daugherty, Lauranne Duquenne, Robert D. Finn, Julian Gough, Daniel Haft, Nicolas Hulo, Daniel Kahn and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Green circle
Published version: archiving allowed
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

The InterPro database (http://www.ebi.ac.uk/interpro/) integrates together predictive models or 'signatures' representing protein domains, families and functional sites from multiple, diverse source databases: Gene3D, PANTHER, Pfam, PIRSF, PRINTS, ProDom, PROSITE, SMART, SUPERFAMILY and TIGRFAMs. Integration is performed manually and approximately half of the total approximately 58,000 signatures available in the source databases belong to an InterPro entry. Recently, we have started to also display the remaining un-integrated signatures via our web interface. Other developments include the provision of non-signature data, such as structural data, in new XML files on our FTP site, as well as the inclusion of matchless UniProtKB proteins in the existing match XML files. The web interface has been extended and now links out to the ADAN predicted protein-protein interaction database and the SPICE and Dasty viewers. The latest public release (v18.0) covers 79.8% of UniProtKB (v14.1) and consists of 16 549 entries. InterPro data may be accessed either via the web address above, via web services, by downloading files by anonymous FTP or by using the InterProScan search software (http://www.ebi.ac.uk/Tools/InterProScan/).