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BioMed Central, Malaria Journal, 1(13), 2014

DOI: 10.1186/1475-2875-13-336

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Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact?

Journal article published in 2014 by Alfredo Mendrone, Crispim Cerutti, José Eduardo Levi, Marcos Boulos, Maria Carmen Arroyo Sanchez ORCID, Rosely dos Santos Malafronte, Silvia Maria Di Santi ORCID, Vicente Odone
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract A study searching for Plasmodium vivax and Plasmodium falciparum DNA among blood donors from the non-endemic area in Brazil reported a rate of 7.41%. This number is at least three times higher than what has been observed in blood donors from the Amazon, an endemic area concentrating >99% of all malaria cases in Brazil. Moreover, the majority of the donors were supposedly infected by P. falciparum , a rare finding both in men and anophelines from the Atlantic forest. These findings shall be taken with caution since they disagree with several publications in the literature and possibly overestimate the actual risk of malaria transmission by blood transfusion in São Paulo city.