Published in
Royal Society of Chemistry, RSC Chemical Biology, 11(3), p. 1342-1358, 2022
DOI: 10.1039/d2cb00187j
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Abilities of the BRICHOS domain to prevent neurotoxicity and fibril formation are dependent on a highly conserved Asp residue
Journal article published in 2022 by
Gefei Chen 
,
Yuniesky Andrade-Talavera ,
Xueying Zhong,
Sameer Hassan,
Henrik Biverstål,
Helen Poska ,
Axel Abelein ,
Axel Leppert,
Nina Kronqvist,
Anna Rising,
Hans Hebert,
Philip J. B. Koeck ,
André Fisahn,
Jan Johansson
,
Yuniesky Andrade-Talavera ,
Xueying Zhong,
Sameer Hassan,
Henrik Biverstål,
Helen Poska ,
Axel Abelein ,
Axel Leppert,
Nina Kronqvist,
Anna Rising,
Hans Hebert,
Philip J. B. Koeck ,
André Fisahn,
Jan Johansson
This paper is made freely available by the publisher.
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Abstract
Activities of the BRICHOS domain against amyloid fibril formation and amyloid-induced neurotoxicity are affected by pH.