Abstract This chapter presents a summary of research priorities for international researchers in the area of late life mood disorders. After a brief discussion on important issues that underlie future research in this area, including sociodemographic changes and advances in technology, it presents a snapshot of current research in late life mood disorders and identifies important gaps. The chapter concludes with recommendations on research priority areas likely to create the most exciting opportunities for the late life mood disorder field in the next 5-10 years. These include more cross disciplinary research, including psycho-social, behavioral and biological approaches; more targeted research into anxiety, including neurological aspects of anxiety advanced through neuroimaging; and translational research that evaluates the effectiveness, cost, and feasibility of treatments for anxiety in a range of settings but particularly primary health settings.