Sex disparities and neutralizing antibody durability to SARS-CoV-2 infection in convalescent individuals
Journal article published in 2021 by
Alena J. Markmann,
Natasa Giallourou,
D. Ryan Bhowmik,
D. Ryan Bhowmik,
Yixuan J. Hou 
,
Aaron Lerner,
David R. Martinez,
Lakshmanane Premkumar,
Heather Root,
David van Duin,
Sonia Napravnik,
Stephen D. Graham,
Quique Guerra,
Rajendra Raut,
Christos J. Petropoulos
and other authors.
,
Aaron Lerner,
David R. Martinez,
Lakshmanane Premkumar,
Heather Root,
David van Duin,
Sonia Napravnik,
Stephen D. Graham,
Quique Guerra,
Rajendra Raut,
Christos J. Petropoulos
and other authors.
This paper is made freely available by the publisher.
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Abstract
In this study, we found that neutralizing antibody responses in COVID-19-convalescent individuals vary in magnitude but are durable and correlate well with receptor binding domain (RBD) Ig binding antibody levels compared to other SARS-CoV-2 antigen responses. In our cohort, higher neutralizing antibody titers are independently and significantly associated with male sex compared to female sex.