Published in

National Academy of Sciences, Proceedings of the National Academy of Sciences, 22(118), 2021

DOI: 10.1073/pnas.2100094118

Links

Tools

Export citation

Search in Google Scholar

Bright daytime light enhances circadian amplitude in a diurnal mammal

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Red circle
Preprint: archiving forbidden
Green circle
Postprint: archiving allowed
Red circle
Published version: archiving forbidden
Data provided by SHERPA/RoMEO

Abstract

Significance Light is an important regulator of endogenous circadian clocks. Regular light–dark cycles set circadian phase to ensure synchrony with external time, while irregular or inappropriate light exposure can disrupt circadian rhythms. We ask here whether light can also impact another key parameter of circadian rhythms, their amplitude, under conditions of stable entrainment. Using a diurnal rodent species and carefully calibrated light stimuli, we show that increasing the intensity of daytime light enhances the reproducibility and robustness of behavioral and physiological rhythms and increases the amplitude of circadian rhythms in electrical activity in the central brain pacemaker. These findings reveal an impact of light on circadian amplitude and highlight the potential importance of daytime light exposure for circadian health.