AbstractObjectiveTo retrospectively analyze the preoperative clinical characteristics and surgical outcomes of evisceration with implantation of an intrascleral silicone prosthesis (EIISP) procedures in dogs and evaluate whether brachycephalic dogs are more prone than non‐brachycephalic dogs to develop postoperative complications after EIISP.Animal studiedNinety‐One dogs (19 of which were brachycephalic) were included.ProceduresMedical records from 2010 to 2019 were reviewed. Signalment, reason for EIISP, postoperative complications, follow‐up time, and postoperative eye appearance were analyzed.ResultsThe most frequently represented breeds were French Bulldog [11/91 (12%) dogs], Jack Russell Terrier [6/91 (7%)], and Shih Tzu [6/91 (7%)]. Brachycephalic dogs were statistically younger than non‐brachycephalic dogs at the time of EIISP (p = 1.61 × 10⁻⁵). Uncontrolled glaucoma was the most common reason for EIISP in both groups. Short‐term complications (from D0 to D15) seen in 7/91 (8%) dogs included epithelial corneal ulcers (n = 3), keratoconjunctivitis sicca (KCS) (n = 2), and prosthesis extrusion (n = 2). Long‐term complications seen in 26/91 (29%) dogs included KCS (n = 11), epithelial corneal ulcers (n = 7), stromal ulcers (n = 3), entropion (n = 4), and prosthesis extrusion (n = 1). Extrusion of the prosthesis occurred twice in eyes that had undergone diode laser transscleral cyclophotocoagulation. The risk of postoperative complications was not significantly different between brachycephalic and non‐brachycephalic dogs (p = .3).ConclusionsBrachycephalic status in dogs does not appear to influence the risk of complications from EIISP. Nevertheless, the present study is a reminder that EIISP focuses on esthetics, and considering the possible complications associated with it, it does not provide a benefit to the patient compared to enucleation.