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Royal Society of Chemistry, Chemical Science, 22(13), p. 6496-6501, 2022

DOI: 10.1039/d1sc04268h

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Quantifying DNA damage on paper sensors via controlled template-independent DNA polymerization

Journal article published in 2022 by Wei Xue, Qiang Zhang, Yangyang Chang, John D. Brennan ORCID, Yingfu Li ORCID, Meng Liu ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Terminal deoxynucleotidyl transferase (TdT) catalyzes template-independent DNA synthesis in a well-controllable mode on paper, allowing absolute quantification of polymetric labeling of a single 3′-OH present on genomic DNA.