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American Association for the Advancement of Science, Science Advances, 42(7), 2021

DOI: 10.1126/sciadv.abj4077

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Progressive alterations in amino acid and lipid metabolism correlate with peripheral neuropathy in Polg <sup>D257A</sup> mice

Journal article published in 2021 by Esther W. Lim ORCID, Michal K. Handzlik ORCID, Elijah Trefts ORCID, Jivani M. Gengatharan ORCID, Carlos M. Pondevida ORCID, Reuben J. Shaw ORCID, Christian M. Metallo ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Alanine accumulation in Polg D257A mice links mitochondrial defects to 1-deoxysphingolipids and peripheral neuropathy.