AbstractMeeting today's major scientific and societal challenges requires understanding dynamics of prosociality in complex adaptive systems. Artificial intelligence (AI) is intimately connected with these challenges, both as an application domain and as a source of new computational techniques: On the one hand, AI suggests new algorithmic recommendations and interaction paradigms, offering novel possibilities to engineer cooperation and alleviate conflict in multiagent (hybrid) systems; on the other hand, new learning algorithms provide improved techniques to simulate sophisticated agents and increasingly realistic environments. In various settings, prosocial actions are socially desirable yet individually costly, thereby introducing a social dilemma of cooperation. How can AI enable cooperation in such domains? How to understand long‐term dynamics in adaptive populations subject to such cooperation dilemmas? How to design cooperation incentives in multiagent learning systems? These are questions that I have been exploring and that I discussed during the New Faculty Highlights program at AAAI 2023. This paper summarizes and extends that talk.