Published in
American Society for Microbiology, Microbiology Spectrum, 3(9), 2021
DOI: 10.1128/spectrum.00338-21
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Amino Acid Metabolism is Significantly Altered at the Time of Admission in Hospital for Severe COVID-19 Patients: Findings from Longitudinal Targeted Metabolomics Analysis
Journal article published in 2021 by
Laura Ansone,
Monta Briviba,
Ivars Silamikelis,
Anna Terentjeva,
Ingus Perkons,
Liga Birzniece,
Vita Rovite,
Baiba Rozentale,
Ludmila Viksna,
Oksana Kolesova,
Kristaps Klavins 
,
Janis Klovins
,
Janis Klovins
This paper is made freely available by the publisher.
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Abstract
Although the host defense mechanisms against SARS-CoV-2 infection are still poorly described, they are of central importance in shaping the course of the disease and the possible outcome. Metabolomic profiling may complement the lacking knowledge of the molecular mechanisms underlying clinical manifestations and pathogenesis of COVID-19.