Published in

National Academy of Sciences, Proceedings of the National Academy of Sciences, 14(119), 2022

DOI: 10.1073/pnas.2114985119

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Optimal deep brain stimulation sites and networks for cervical vs. generalized dystonia

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Significance We studied deep brain stimulation effects in two types of dystonia and conclude that different specific connections between the pallidum and thalamus are responsible for optimal treatment effects. Since alternative treatment options for dystonia beyond deep brain stimulation are scarce, our results will be crucial to maximize treatment outcome in this population of patients.