Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes

Le Guen, Yann; Guen, Yann Le; van der Flier, Wiesje; Luo, Guo; Ambati, Aditya; Damotte, Vincent; Jansen, Iris; Yu, Eric; Nicolas, Aude; de Rojas, Itziar; Leal, Thiago Peixoto; Miyashita, Akinori; Bellenguez, Céline; Lian, Michelle Mulan; Parveen, Kayenat; Morizono, Takashi; Park, Hyeonseul; Grenier-Boley, Benjamin; Naito, Tatsuhiko; Kucukali, Fahri; Küçükali, Fahri; Talyansky, Seth D.; Yogeshwar, Selina Maria; Sempere, Vicente; Satake, Wataru; Alvarez, Victoria; Arosio, Beatrice; Belloy, Michael E.; Benussi, Luisa; Boland, Anne; Borroni, Barbara; Bullido, María J.; Caffarra, Paolo; Clarimon, Jordi; Daniele, Antonio; Darling, Daniel; Hort, Jakub; Debette, Stéphanie; Jung, Yoo Jin; Maria Garcia-Alberca, Jose; Garcia-Gonzalez, Pablo; Deleuze, Jean-François F.; Jürgen, Deckert; Kern, Silke; Dichgans, Martin; Kuulasmaa, Teemu; Lee, Kun Ho; Dufouil, Carole; Lin, Ling; During, Emmanuel H.; Masullo, Carlo; van Swieten, John; Mecocci, Patrizia; Düzel, Emrah; Mehrabian, Shima; Galimberti, Daniela; de Mendonça, Alexandre; Garcia-Ribas, Guillermo; Boada, Mercè; Mir, Pablo; Moebus, Susanne; Moreno, Fermin; Nacmias, Benedetta; Giedraitis, Vilmantas; Nicolas, Gael; Niida, Shumpei; Goldhardt, Oliver; Nordestgaard, Børge G.; Graff, Caroline; Papenberg, Goran; Papma, Janne; Grünblatt, Edna; Parnetti, Lucilla; Pasquier, Florence; Hanon, Olivier; Pastor, Pau; Hausner, Lucrezia; Peters, Oliver; García-Alberca, José María; Pijnenburg, Yolande A. L.; Heilmann-Heimbach, Stefanie; Puerta, Raquel; Piñol-Ripoll, Gerard; Holstege, Henne; García-González, Pablo; Popp, Julius; Pérez-Tur, Jordi; Porcel, Laura Molina; Rainero, Innocenzo; Ramakers, Inez; Jordi Perez-Tur, Raquel Puertaj; Real, Luis M.; Riedel-Heller, Steffi; Rodriguez-Rodriguez, Eloy; Ross, Owen A.; Royo, Jose Luís; Rujescu, Dan; Scarmeas, Nikolaos; Scheltens, Philip; Scherbaum, Norbert; Schneider, Anja; Seripa, Davide; Skoog, Ingmar; Solfrizzi, Vincenzo; Spalletta, Gianfranco; Squassina, Alessio; Sanchez-Valle, Raquel; Sánchez-Valle, Raquel; Tan, Eng-King K.; Tegos, Thomas; Teunissen, Charlotte; Thomassen, Jesper Qvist; Tremolizzo, Lucio; Vyhnalek, Martin; Verhey, Frans; Waern, Margda; Wiltfang, Jens; Zhangc, Jing; Zhang, Jing; Zetterberg, Henrik; Blennow, Kaj; He, Zihuai; Williams, Julie; Amouyel, Philippe; Jessen, Frank; Kehoe, Patrick G.; Andreassen, Ole A.; Van Duin, Cornelia; Tsolaki, Magda; Sanchez-Juan, Pascual; Sánchez-Juan, Pascual; Frikke-Schmidt, Ruth; Sleegers, Kristel; Todau, Tatsushi; Toda, Tatsushi; Zettergren, Anna; Ingelsson, Martin; Okada, Yukinori; Rossi, Giacomina; Hiltunen, Mikko; Gim, Jungsoo; Ozaki, Kouichi; Sims, Rebecca; Foo, Jia Nee; Ikeuchi, Takeshi; Ramirez, Alfredo; Mata, Ignacio; Ruiz, Agustín; Gan-Or, Ziv; Lambert, Jean-Charles C.; Greicius, Michael D.; Mignot, Emmanuel

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Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes

Journal article published in 2023 by Yann Le Guen, Yann Le Guen, Wiesje van der Flier, Guo Luo, Aditya Ambati, Vincent Damotte, Iris Jansen, Eric Yu, Aude Nicolas, Itziar de Rojas, Thiago Peixoto Leal, Akinori Miyashita, Céline Bellenguez, Michelle Mulan Lian, Kayenat Parveen and other authors.

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