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American Society for Microbiology, Applied and Environmental Microbiology, 3(89), 2023
DOI: 10.1128/aem.01963-22
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A Fungal P450 Enzyme from Fusarium graminearum with Unique 12β-Steroid Hydroxylation Activity
Journal article published in 2023 by
Ling Wang,
Xiaowei Wu,
Chenghua Gao,
Lingrui Wei,
Qian Li,
Aitao Li 
This paper is made freely available by the publisher.
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Abstract
Regioselective and stereoselective hydroxylation is of vital importance in the functionalization of steroids, which remains challenging in organic synthesis. In particular, the C12-hydroxy steroids play a significant role in the synthesis of many important steroidal drugs.